A new source of aging?
J Cosmet Dermatol. 2009 Jun; 8(2): 77-82
Knaggs H
There has been a considerable increase in understanding how skin ages, along with significant progress toward the correction and prevention of the visible signs of aging. However, there are still many unknown factors regarding why we age – and why we all seem to age differently. An area of high interest is the biological or intrinsic processes that affect our appearance over time. This article describes a recent discovery of a membrane bound enzyme proven to be present in skin and increases its activity as biological age increases. The enzyme is located on the external surface of both fibroblast and keratinocytes, and generates free radicals. Therefore, as we age there appears to be a biological mechanism that further increases the production of free radicals. Additionally, there appears to be a relationship between activity of the enzyme and appearance. Data showed that subjects who look younger than their biological age had lower enzyme activity and conversely, subjects who looked older than their biological age had higher enzyme activity. Free radicals are believed to be a major contributing factor in the production of fine lines and wrinkles by destroying the collagen and elastin network keeping skin supple and firm.
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Is a sample size gathered from 42 people of the same age a reliable source of data? Why/why not?
Is a sample size gathered from 42 people of the same age a reliable source of data? Why/why not?
No, because that particular sampling group tests people who are alike and may have the same interests (thus giving you the same general results for each one). You would need to test people randomly from all different ages.
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It depends on the population you are sampling. If you are sampling 42 from a population of 20 million then it is not reliable. If your sampling 42 from a population of 200 then your sample is more reliable.
It also depends on what you are trying to achieve. If you want to determin the opinions of a certain age group then your sample is perfect. If you want to determin the opinions of the genereal populus then you sample is not useful.
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